FlowFuel Trifecta Testing™
Stop Guessing.
Start Knowing What Your Body Actually Needs.
Three at-home tests. One written plan. Know which supplements are worth your money. Get the ones matched to you.
In short FlowFuel.Pro offers three at-home wellness assessments: metabolomics from a urine sample, GI from a stool sample and genomic from a cheek swab. Each one is reviewed by our clinical nutritionist and turned into a written plan. One assessment is $495 and FlowFuel Trifecta Testing is $2,500. Not available in New York, New Jersey, Rhode Island or U.S. territories.
How testing works
From kit to written plan in five steps. 49 seconds.
Sound Familiar?
You're Doing Everything Right. You Still Feel Off.
You train, eat clean and track everything, but your wearable shows the data, not what to do about it. The afternoon crash still hits. Sleep doesn't leave you rested. Focus slips. You add another supplement. Nothing changes.
The problem was never your effort. You've been optimizing in the dark, almost blind. FlowFuel turns the lights on.
Energy That Won't Stick
Some days you're sharp, some days you're running on empty, and clean eating and early nights don't change it. Your metabolomics results show how your body is making and using energy.
For women, the Hormone add-on is top tier. Without it, you can't see exactly what you need.
See the Hormone add-on ($500) →Brain Fog & Mood Drift
Serotonin, dopamine and GABA leave markers you can measure. Your nutritionist reads them with the rest of your results and matches nutrients to what they show.†
A Gut That Keeps You Guessing
Bloating comes and goes, foods suddenly don't sit right, and digestion changes week to week. Your GI results map the microbes in your gut by DNA, and your plan follows three steps: Weed. Seed. Feed.†
A Cabinet of Guesses
You've spent hundreds of dollars on supplements bought on a podcast tip or a friend's advice, with no way to know if any of it fits you. Your genomic results help show which nutrient forms suit your body.
Why It Works
Real Data. Real Review. Real Fuel.
Most "wellness" is a guess in a nicer bottle. FlowFuel is built on your actual biology: three at-home tests that read your metabolism, your gut and 3,000+ genetic markers. Our clinical nutritionist reviews every result, and you get a plan you don't have to assemble yourself. That's the difference between hoping and knowing.
The Guessing Game
- Supplements picked from ads, podcasts and labels
- One-size-fits-all supplement formulas
- Guessing based on symptoms alone
- No genetic or metabolic context
- The same advice you've heard a hundred times
FlowFuel Trifecta Testing
- Your own metabolism, gut and DNA results
- A plan built for one person: you
- Data-driven decisions, zero guessing
- Read by a nutritionist, signed off by Jamie
- Coaching that keeps you consistent
Three tests. One plan.
What each test looks at and how they are read together. 40 seconds.
Three Tests. One Complete Picture of Your Biology.
FlowFuel Trifecta Testing is FlowFuel.Pro's core functional wellness assessment — three complementary tests that map your metabolism, your gut microbiome, and your genetic blueprint simultaneously.
Your metabolism shows how your body is making and using energy right now. Your gut shows what lives there and how well you break down food. Your genes show which nutrient forms suit you. Separate, each test gives you a piece. Together, they give you the whole picture, and your plan names the supplements worth your money and the ones you can skip.†
Every result is reviewed by our clinical nutritionist. You get one written plan, not a raw report, and Jamie Mentzer, founder of FlowFuel.Pro and BioFlow.Pro, reviews and signs off on it personally.
Your Three-Test Protocol
Trifecta Metabolomics Assessment™
Urine · Maps energy, neurotransmitters, detox, B-vitamin status, and microbial metabolites across 60+ biomarkers.
Trifecta GI Assessment™
Stool · DNA/PCR analysis of your gut microbiome, from bacteria and fungi to digestion markers, turned into a three-step gut plan: Weed. Seed. Feed.
Trifecta Genomic Assessment™
Cheek swab · Your DNA doesn't change, so you test it once: 3,000+ genetic markers across 8 health areas, including methylation and detox.
The Three Tests
What Each Test Reveals — and Why It Matters
This is not a test you interpret alone. Every order includes the lab work, a review by our clinical nutritionist and Jamie's personal sign-off, built in at no extra fee.
Trifecta Metabolomics Assessment™
- →Energy Metabolism — Krebs cycle, glycolysis, fatty acid oxidation, ketone status
- →B-Vitamin Status — B1, B2, B3, B5, B6, B12, folate, and biotin functional markers
- →CNS Neurotransmitters & Cortisol — serotonin turnover, dopamine, GABA, free cortisol†
- →Detox and Oxidative Stress Markers — Phase I & II detox markers, oxidative stress and fungal markers
- →Gut Microbial Metabolites — bacterial and fungal population signatures via urine organic acids
Trifecta GI Assessment™
- →Beneficial bacteria populations — Lactobacillus, Bifidobacterium, Akkermansia and more
- →Opportunistic bacteria and other flagged microbes — measured by DNA, not culture estimates
- →Fungal presence — including Candida species and other fungi
- →Digestive function — enzyme activity and nutrient absorption markers
- →Gut-wall integrity signals — inflammatory and immune response markers
- →Parasite and protozoa markers — measured by DNA
Trifecta Genomic Assessment™
- →Methylation — MTHFR and related SNPs affecting B-vitamin use and detoxification
- →Detoxification — CYP450 variants and Phase I/II liver detox capacity
- →Cognitive Health — genetic markers linked to focus and memory
- →Inflammatory Status — variants modulating your inflammatory response profile
- →Endocrine Health — hormone metabolism and receptor sensitivity genetics
- →Gastrointestinal Health — genetic factors in gut function and microbiome resilience
- →Structural Health — collagen synthesis and mineral absorption genetics
- →Aging & Cellular Repair — oxidative stress and longevity-related genetic factors
The FlowFuel Way: Test. Review. Protocol. Fuel.
Test
Order your test or bundle, then collect at home in minutes: urine, stool or a cheek swab. Prepaid return packaging is included.
Review
A lab runs your sample, and our clinical nutritionist reads your results alongside your full health history.
Protocol
You get one written plan built from your results and signed off by Jamie. With the GI test, your gut plan follows three steps: Weed. Seed. Feed.†
Fuel
Fuel your body from your plan. Coaching keeps you consistent, retests show what changed, and when you're ready, Customized Nutrition turns it all into one formula.†
Clinical Standards
Every Protocol Reviewed Before It Reaches You
Trifecta Testing is not a self-service report. Our clinical nutritionist reads every result and Jamie signs off on every plan before it reaches you, because a supplement plan is only as good as the people reading your results.
Testing is conducted by CLIA-certified, accredited laboratories. Results are interpreted through a systems-biology approach — connecting pathway patterns, not just flagging isolated out-of-range values.
CLIA-Certified Laboratory Analysis
All tests processed by accredited, CLIA-certified labs. Research-grade analysis — not reference-range-only interpretation.
Licensed Physician Order
All lab testing is ordered and authorized through an independent network of licensed physicians, as required by law. A licensed provider reviews your order before your kit ships.
Clinical Nutritionist Integration
Your prior labs, bloodwork and health history are reviewed by our clinical nutritionist, so your plan fits your full picture, not just today's test.
Personal Review by Jamie Mentzer
Jamie, founder of FlowFuel.Pro and BioFlow.Pro, personally reviews and signs off on every Trifecta Testing plan before it reaches you.
Choose Your Path
Where Do You Want to Start?
Not Sure Where to Start?
Do You Actually Need Coaching?
Take this 60-second quiz to see whether the tests alone are enough or you'd do better with a coach in your corner for three months.
The True Cost of Guessing
Interactive ROI Calculator
Many people spend more than they realize on trial and error. Use this calculator to estimate what you have spent on supplements and therapies chosen without data.
Gadgets, drips and other add-ons.
Total Spent Guessing
$15,000
If 60% Were Guesswork
$9,000
Cost of FlowFuel Trifecta Testing
$2,500
Guesswork Minus Testing
$6,500
A hypothetical illustration based on the numbers you enter, not a promise of savings. Your costs will differ.
Illustration only, based on the numbers you enter. Your costs will differ.
Pricing & Programs
Start With What Your Body Actually Needs
Your metabolism, gut and genes tell one connected story. Test all three and your plan sees the whole picture.
Complete Three-Test Protocol
FlowFuel Trifecta Testing
All three at-home tests, one written plan and 3 months of coaching. Each week you meet with your coach, and each month with Jamie. You collect all three samples at home in minutes, and your written plan usually arrives 3 to 5 weeks after you order.
$2,500 vs $2,985 when the three tests are bought one at a time with coaching
Get FlowFuel Trifecta Testing — $2,500Your metabolism, gut and hormones change over time. For the year after your first test, retests of your Metabolomics, GI and Hormone assessments are $250 each, so your plan can change as you do. Your DNA doesn't change, so the Genomic test never needs a retest.
Subscribe & Save: Enroll in a retest subscription and buy retest packs for $250 each — the lowest retest price available.
Everything included:
- Trifecta Metabolomics, GI and Genomic Assessments™
- One written plan across all three results, including a gut plan: Weed. Seed. Feed.
- Clinical nutritionist review of your full health history
- Jamie's protocol review and sign-off
- In-person results meeting with Jamie (Laguna Beach)
- 3 months of coaching: 1 session a week with your coach
- 1 session a month with Jamie
- Flow Friends community
Test Your Body. Train Your State.
Training with BioFlow.Pro? Add FlowFuel Trifecta Testing to your BioFlow training and the two synchronize: testing shows what your body is working with, and training teaches you to steady your state. Want it all? BioFlow Trifecta Training, all three Deep Dives and FlowFuel Trifecta Testing come together in one package ($7,500).
Add Testing to My BioFlow PlanSingle Test with Coaching
Single Test + 3-Month Coaching
Start with the test that matches your biggest concern. You get your nutritionist's review, an in-person kickoff with Jamie and 3 months of coaching to put your plan to work.
One test covers one part of the picture. Add the other two within 60 days and everything you paid counts toward FlowFuel Trifecta Testing. You never pay twice.
Choose one: Metabolomics, GI or Genomic
Everything included:
- Your chosen Trifecta test + lab analysis
- Personalized report and protocol
- Clinical nutritionist review
- Jamie's personal protocol review
- In-person kickoff with Jamie (Laguna Beach)
- 3 months of coaching: 1 session a week with your coach
- 1 session a month with Jamie
- Flow Friends community
Build Your Own
Custom Bundle Calculator
Select the tests and add-ons you need. Note: FlowFuel Trifecta Testing (3 tests + coaching) automatically applies a bundle discount.
1. Select Tests ($495 each)
2. Add Coaching? (+$500 per test)
3. Hormone Add-on (+$500)
You never pay twice
Move up within 60 days of your last purchase and everything you've paid counts toward the higher level.
The 3-Month Coaching Curriculum
A structured, data-driven approach to integrating your lab results and locking in sustainable habits.
Month 1: Discovery & Integration
- Deep dive into lab results and health history
- Your written plan, including gut steps from the GI test: Weed. Seed. Feed.
- Establishing baseline metrics and daily non-negotiables
Month 2: Adaptation & Optimization
- Weekly check-ins to keep your plan on track
- Clearing roadblocks and fine-tuning amounts with your nutritionist
- Biofeedback tracking and lifestyle integration
Month 3: Mastery & Continuity
- Reviewing how you feel and what your numbers show
- Preparing for re-testing and tracking progression
- Transitioning to sustainable, long-term maintenance
BioFlow VIP
BioFlow VIP is a year with Jamie himself, by application. Your FlowFuel testing and your BioFlow training synchronize into one plan, and Jamie coaches you through all of it.
Flow + Fuel ($7,500) and a Jamie Kickoff ($2,500) equal $10,000 on their own. BioFlow VIP Elite ($10,000/yr) includes both plus 12 months of weekly 1:1 with Jamie, quarterly retests, and priority support at zero extra cost in your first year.
BioFlow VIP Elite
Weekly 1:1 with Jamie
- ✓Everything in Flow + Fuel ($7,500 on its own)
- ✓Jamie Kickoff included
- ✓Weekly 1:1 sessions with Jamie for 12 months
- ✓Quarterly retests
- ✓Priority support
BioFlow VIP Concierge
Direct priority access to Jamie
- ✓Everything in BioFlow VIP Elite
- ✓Customized Nutrition Formula ($5,000 on its own)
- ✓$2,500 supplement credit
- ✓VIP event access
BioFlow VIP In-Home
On-demand concierge
- ✓Everything in BioFlow VIP Concierge
- ✓$10,000 supplement credit
- ✓In-home setup and assessment
- ✓Sourced and vetted local trainers
- ✓Coordinated BioFlow team and DNA concierge
Want time with Jamie without VIP?
Jamie Kickoff · $2,500 · Add to any BioFlow level
- ✓3 months with Jamie, starting with a deep-dive consultation
- ✓Two follow-up integration sessions
- ✓Personalized action plan
- ✓Email support
Get the Full Breakdown
Leave your details and our team will follow up with the full breakdown of the three tests and how your written plan is built.
Order FlowFuel Trifecta Testing
All three at-home tests, one written plan and 3 months of coaching ($2,500)
Referred by a doctor? Enter your partner code at checkout for special pricing.
Frequently Asked Questions
Start Knowing
Ready to Fuel the Body You Actually Have?
Don't spend another year guessing. We read your metabolism, your gut and your genes together and turn them into one plan built for you, reviewed by our clinical nutritionist and signed off by Jamie. Pick the test that fits your goal, or book a free Discovery Call and we'll point you to the right first step.
Get FlowFuel Trifecta Testing — $2,500† These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. All laboratory testing is ordered and authorized through an independent licensed physician network, as required by law. Your order is reviewed by a licensed provider before your kit ships.
Trifecta Testing™ assessments are currently not available to residents of New York, New Jersey, Rhode Island or U.S. territories due to regulations governing direct-access laboratory testing. Some content and communications are prepared with AI assistance and reviewed by our clinical team prior to publication. Individual results will vary.